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Diabetic neuropathy: Types & Causes





Diabetic neuropathy is a type of nerve damage that can occur as a complication of diabetes. It happens due to prolonged high blood sugar levels, which can injure the nerves throughout the body. The condition most commonly affects the peripheral nerves, which are the nerves outside the brain and spinal cord. Diabetic neuropathy can lead to various symptoms and complications, depending on the nerves affected. There are several types of diabetic neuropathy:

  • Peripheral neuropathy: This is the most common type and affects the nerves in the feet, legs, hands, and arms. Symptoms may include:

    • Numbness or reduced sensation

    • Tingling or burning sensation

    • Sharp, jabbing pains

    • Extreme sensitivity to touch

    • Muscle weakness and loss of coordination

    • Ulcers or sores on the feet or legs, which can become infected if not properly cared for

    • Changes in foot shape and deformities

  • Autonomic neuropathy: This type affects the autonomic nerves, which control involuntary bodily functions such as heart rate, blood pressure, digestion, and bladder function. Symptoms may include:

    • Abnormal heart rate or rhythm

    • Orthostatic hypotension (dizziness or fainting upon standing)

    • Gastroparesis (delayed stomach emptying), leading to nausea, vomiting, and bloating

    • Diarrhea or constipation

    • Bladder problems, such as urinary incontinence or difficulty emptying the bladder

    • Sexual dysfunction, including erectile dysfunction in men and vaginal dryness or difficulty achieving orgasm in women

  • Proximal neuropathy: Also known as diabetic amyotrophy, this type affects the nerves in the thighs, hips, buttocks, or legs. Symptoms may include:

    • Severe pain or burning sensation in the affected areas

    • Weakness and atrophy (muscle wasting) of the affected muscles

    • Difficulty rising from a sitting position

    • Abdominal swelling

  • Focal neuropathy: This type involves damage to specific nerves, resulting in sudden and severe symptoms. Focal neuropathy can affect any part of the body, such as the head, torso, or leg. Symptoms depend on the affected nerve and may include:

    • Intense pain in the chest, stomach, or lower back

    • Pain in and around the eyes

    • Bell's Palsy (sudden weakness or paralysis of facial muscles)

    • Double vision or other vision problems


Diabetic neuropathy: Types & Causes

Causes of diabetic neuropathy:


The exact mechanisms behind diabetic neuropathy are not fully understood. However, prolonged high blood sugar levels (hyperglycemia) are believed to play a significant role in damaging the nerves. Other factors that may contribute to the development of diabetic neuropathy include:

  • Nerve inflammation and damage due to metabolic factors related to diabetes

  • Genetics and family history of neuropathy

  • Smoking and alcohol abuse, which can worsen nerve damage

  • Duration of diabetes - the risk of neuropathy increases with the duration of diabetes

  • Obesity and hypertension, which can exacerbate nerve damage

  • Autoimmune factors - the body's immune system may attack and damage nerves in some cases


Proper management of diabetes, including maintaining blood sugar levels within target ranges, is crucial in preventing or delaying the onset and progression of diabetic neuropathy. If you experience any symptoms of diabetic neuropathy, it's essential to consult with a healthcare professional for evaluation and appropriate management. Early intervention can help prevent further complications and improve quality of life.



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